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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYN3 All Species: 12.42
Human Site: T85 Identified Species: 30.37
UniProt: O14994 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14994 NP_003481.3 580 63303 T85 M E P P G P S T P I V Q R P R
Chimpanzee Pan troglodytes XP_515096 579 63181 T85 M E P P G P S T P I V Q R P R
Rhesus Macaque Macaca mulatta XP_001086745 582 63133 L86 G S S F F S S L S Q A V K Q T
Dog Lupus familis XP_850873 579 63100 A85 M E P P G P S A P I I Q R P R
Cat Felis silvestris
Mouse Mus musculus Q8JZP2 579 63326 T85 M E P P T P V T P V V Q R P R
Rat Rattus norvegicus O70441 579 63330 T85 M E P P T P V T P V V Q R P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510451 589 64300 P85 L S E P A G S P A P I P Q K P
Chicken Gallus gallus
Frog Xenopus laevis NP_001079204 580 63774 P85 L V E Q T G A P A T P V V L K
Zebra Danio Brachydanio rerio NP_001119909 670 72335 G85 F N E A T E R G I G S G N A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24546 1025 107509 A106 V Q S L T G A A R D Q G A S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 60.6 93.9 N.A. 92.4 92 N.A. 74.8 N.A. 68 52.8 N.A. 27.1 N.A. N.A. N.A.
Protein Similarity: 100 99.6 74.2 95.5 N.A. 95.1 95.3 N.A. 82.8 N.A. 79.1 65.9 N.A. 37.7 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 80 80 N.A. 13.3 N.A. 0 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 86.6 86.6 N.A. 33.3 N.A. 20 6.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 20 20 20 0 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 50 30 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 30 30 0 10 0 10 0 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 30 20 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 20 % K
% Leu: 20 0 0 10 0 0 0 10 0 0 0 0 0 10 0 % L
% Met: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 50 60 0 50 0 20 50 10 10 10 0 50 10 % P
% Gln: 0 10 0 10 0 0 0 0 0 10 10 50 10 10 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 0 0 0 50 0 50 % R
% Ser: 0 20 20 0 0 10 50 0 10 0 10 0 0 10 0 % S
% Thr: 0 0 0 0 50 0 0 40 0 10 0 0 0 0 10 % T
% Val: 10 10 0 0 0 0 20 0 0 20 40 20 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _